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《毒理学百科(精选卷)》
作者:(美)威克斯勒 主编
出版社:科学出版社 出版日期:2007-9-1
ISBN:9787030199331 定价:元
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    本书为毒理学医学类百科全书,主要包含了毒理学的重要概念,如计量效应、作用机制、试验程序、靶位等,还收集了与毒理学相关的历史、法律、条例、数据库。对毒理学家会相当有用,同时也适用于医学、法律、科学工作者查阅。

     内容简介

    本书为毒理学医学类百科全书,主要包含了毒理学的重要概念,如计量效应、作用机制、试验程序、靶位等,还收集了与毒理学相关的历史、法律、条例、数据库。对毒理学家会相当有用,同时也适用于医学、法律、科学工作者查阅。

    本书是在原版Encyclopedia of Toxicology(2nd edn)的基础上对词条进行的分类重排。编成三卷,分别为精选卷、拓展卷与社科管理卷,更加适合国内读者阅读。本书涵盖了毒理学研究的各个领域,从基础到前沿,甚至一些尚存争议的问题也包含其中。

    第二版百科全书汇集了392作者提供的1057条目录,而第一版只包括200名作者提供的749条目录。实际上,第一版中所有条目的内容在第二版中都得到了充实,而某些条目则完全进行了更新。在第二版中新出现的308个条目中,包括鸟类生态毒理学、基准剂量、杀虫剂、计算机毒理学、致癌效力因素、代谢组学、化学事件、蒙地卡罗分析、非致死性化学武器、无脊椎动物生态毒理学、药物滥用、癌症化疗因子和消费产品等等。许多针对特殊化学物的条目都是全新的,而书中搜录的国际组织也得到了很大的扩展。某些条目罗列了许多著名的毒物中毒相关事件:如美国拉夫运河事件、泰晤士海滩事件、切尔诺贝利事件和三里岛事件等。另外许多条目涉及毒理学知识的社会应用,如文化毒理学、环境犯罪、著名投毒者和中毒可件、古代化学生物战以及美国环境运动历史等。因此,新版的毒理学百科全书在长度、广度、以及深度上都对毒理学的许多方面进行了更广泛和深入的概述。

     目录

    Aberrations of Chromosomes(染色体畸变,染色体异常)see Chromosome Aberrations

    Absorption(吸收)Jules Brodeur and Robert Tardif

    Acceptable Daily Intake(ADI)(每日允许摄入量)Jaya Chilakapati and Harihara M Mehendale

    Aggregate Exposures(累积照射)Jeffrey H Driver

    Ames Test(埃姆斯试验)Robin C Guy

    Analytical Toxicology(分析毒理学)Shayne C Gad

    Aneuploidy(非整倍性)David A Eastrnond

    Animal Models(动物模型)Shayne C Gad

    Aquatic Ecotoxicology(水域生态毒理学、水域生态毒物学)see EcotoxicologyAquatic

    Aquatic Toxicity Testing(水生毒性试验)see Toxicity Testing,Aquatic

    Avian Ecotoxicology(鸟类生态毒理学)see Ecotoxicology,Avian

    Behavioral Toxicity Testing(行为中毒试验、行为毒性试验)see Toxicity Testing Behavioral

    Behavioral Toxicology(行为毒理学)Deborah A Cory-Slechta

    Benchmark Dose(基准剂量)Qiyu Jay Zhao

    Biological Exposure Index(生物照射)Alan J Weinrich

    Biomarkers,Environmental(环境生物标记),Lee R Shugart

    Biomarkers,Human Health(人类健康生物标记)Rogene F Henderson

    Biotrans{ormation(生物转化)Tanya C McCarthy and Christopher J Sinai

    Carcinogen-DNA Adduct Formation and DNA Repair(致癌原一DNA加合物形成与DNA修复)Ainsley Weston andMiriam C Poirier

    Carcinogenesis(致癌作用)David E Malarkey and Robert R Maronpot

    Carcinogenicity Toxicity Testing(致癌毒性试验)see Toxicity Testing Carcinog-enesis

    Chemical-Specific Adjustment Factor(CSAF)(化学特异性调节因子)Bette Meek

    Chromosome Aberrations(染色体畸变、染色体异常)Antone L Brooks

    Combustion Toxicology(燃烧毒理学)Barbara C Levin and Erica D Kul igowski

    Common Mechanism of Toxicity(主要毒性机理)Beth Mileson

    Computational Toxicology(计算机毒理学)S Satheesh Anand and Harihara M Meh-endale

    Cumulative Risk Assessment(累积危险评价)Jeffrey H Driver

    Deoxyribonucleic Acid(脱氧核糖核酸)see Aneuploidy;Carcinogen-DNA AdductFormation and DNA Repair;Chromosome Aberrations;DNA Phosphoramidites;Genetic Toxicology;Genomics.Toxicogenomics

    Dernlal Toxicity Testing(皮肤毒性试验)see Toxicity Testing,Dermal

    Development Toxicity Testing(发育毒性试验)see Toxicity Testing,Developmental

    Developmental Toxicology(发育毒理学)Calvin C Willhite and Philip E Mirkes

    DNA(脱氧核糖核酸)see Aneuploidy;Carcinogen-DNA Adduct Formation and

    DNA Repair;Chromosome Aberrations;DNA Phosphoramidites;Genetic To-

    xicology;Genonlics,Toxicogenomics;Molecular Toxicology~Recombinant DNA

    Technology Toxicity Testing.Mutagenicity

    DNA Adduct(DNA加合物)see Carcinogen-DNA Adduct Formation and DNA Repair

    DNA Phosphoramidites(DNA亚磷酰胺)Sang-Tae Kim

    DNA Repair(DNA修复)see Carcinogen-DNA Adduct Formation and DNA Repair

    Dominant Lethal Tests(显性致死试验)Samantha E Gad

    Dose-Response Relationship(剂量效应关系)Samantha E Gad

    Ecotoxicology(生态毒理学、生态毒物学)Chris Theodorakis

    Ecotoxicology,Aquatic(水域生态毒理学)Yuan Zhao and Michael C Newman

    Ecotoxicology,Avian(-g类生态毒理学)Pierre Mineau1

    Ecotoxicology,Genetic(遗传生态毒理学)Wendy L Rose and Susan L Anderson

    Ecotoxicology,Invertebrate(无脊椎动物生态毒理学)Pawel J Migula

    Ecotoxicology,Terrestrial(陆地生物生态毒理学)Anne Fairbrother and Bruce Hope

    Ecotoxicology,Wildlife(野生动植物生态毒理学)Richard S Halbrook

    Environmental Hormone Disruptors(环境激素破坏剂)Lorenz Rhomberg and MaraSeeley

    Environmental Toxicology(环境毒理学)Chris Theodorakis

    Exposure(暴露)Gary Whitmyre and Sam Kacew

    Exposure Assessment[(危害)暴露评估]Gary Whitmyre and Jeffrey H Driver

    Exposure Criteria(暴露标准)Andrew Maier

    Eye Irritancy Testing(眼球刺激试验)Samantha E Gad

    Food Safety and Toxicology(食品安全与毒理学)Michael Bolger and Clark D Carr_ington

    Foreign Body Response(异物反应)Shayne C Gad

    Forensic Toxicology(法医毒理学)Felix K Adatsi

    Genetic Ecotoxicology(遗传生态毒理学)see Eeotoxicology,Genetic

    Genetic Toxicology(遗传毒理学)Joseph R Landolph

    Genomics,Toxicogenomics(基因组、毒物基因组)Kartik Shankar and Harihara M Mehendale

    GOOd Clinical Practice(GcP)(药物临床试验管理规范)Sharmilee P Sawant and Harihara M Mehendale

    Good LaboratorY Practices(GLP)(良好实验室管理规范)Robin C Guy

    Hormesis(毒物刺激作用)Elyisha A Hanniman and Christopher J Sinai

    Hormone Disruptors(激素破坏剂)see Environmental Hormone Disruptors

    Host-Mediated Assay(宿主间介试验)David A Eastmond

    Hypersensitivity,Delayed Type(迟发型超敏反应)Leigh Ann Burns-Naas

    Immediately Dangerous to Life or Health(IDLH)Values(即刻性损伤或致死浓度) Alan J Weinrich

    Inhalation Testing(吸入试验)see Toxicity Testing,Inhalation

    Interactions(相互作用)see Interactive Toxicity

    Interactive Toxicity(相互作用毒性)S Satheesh Anand and Harihara M Mehendale

    Irritation Testing(刺激试验)see Toxicity Testing,Irritation

    LD50/LCs0(Lethal Dosage 50/Lethal Concentration 50)(半数致死剂量)Shayne C Gad

    Lethal,Dosage Or Concentration(致死剂量/浓度)see LD50/LC50(Lethal Dosage

    50/Lethal Concentration 50)

    Levels of Effect in Toxicological Assessment(毒物效应评价水平)Michael Dourson

    Lowest-Observed~Adverse-Effect Level(观察到副作用的最小剂量)see Levels of

    Effect in Toxicological Assessment

    Lowest-Observed-Effect Level(观察到作用的最小剂量,最低作用水平)see Leve-

    Is of Effect in Toxicological Assessment

    Margin of Exposure(MOE)(暴露界限)Udayan M Apte and Harihara M Mehendale

    Maximum Allowable Concentration(MAC)(最高容许浓度)Shayne C Gad

    Maximum T01erated Dose(MTD)(最大耐受剂量)Shayne C Gad

    Mechanisms of Toxicity(毒性机制)Sanjay Chanda and Harihara M Mehendale

    Mode of Action(作用方式)Lynne Haber

    Models(模型)see Animal Models

    Modifying Factors of Toxicity(毒性修饰因子)Frank C Lu and Sam Kacew

    M01ecular Toxic010gy_Recombinant DNA Technology(分子毒理学一重组DNA技术)

    Evan A Thackaberry

    Mouse Lymphoma Assay(小鼠淋巴瘤测定)Robin C Guy

    Neoplasia(瘤形成)see Carcinogenesis

    Neurotoxicity(神经毒性)Peter S Spencer and Pamela J Lein

    Nonionizing Radiation(非电离辐射)see Radiation Toxicology,Ionizing and Non-

    ionizing

    No-Observed-Adverse-Effect Level(未观察到的副作用水平)see Levels of Effect

    in Toxicological Assessment

    No-Observed-ElfeCt Level(未观察到的效应水平)see Levels of Effect in Toxicol-

    ogical Assessment

    Occupational Exposure Limits(职业性暴露极限)Andrew Maier

    Occupational Toxicology(职业毒理学)Elizabeth V Wattenberg3

    Ototoxicity(耳毒性)Michael J Sullivan

    PharmacokinetiCS/Toxicokinetics(药物代谢动力学/毒物代谢动力学)Robert Tardif

    and Jules Brodeur

    Pharmacology and Safety(安全药理学)see Safety Pharmacology(拓展卷)

    Radiation Toxicology,Ionizing and Nonionizing(电离辐射与非电离辐射毒理学)

    Bobby R Scott and Raymond A Guilmette

    Recombinant DNA(重组DNA)see Molecular Toxicology-Recombinant DNA Tee-

    hnology

    Safety Testing,Clinical Studies(临床研究安全试验)Alessandra Pagnoni366

    Sensitivity Analysis(灵敏度分析)Virginia Lau

    Sensitization Testing(敏感试验、致敏试验)see Toxicity Testing,Sensitization

    Short-Term Exposure Limit(短期暴露限度)see Occupational Exposure Limits

    Subchronic Toxicity(亚慢性毒性)see Toxicity,Subchronic

    Teratology(畸形学)see Developmental Toxicology

    Teratology Testing(致畸实验)see Toxicity Testing,Developmental

    Terrestrial Ecotoxicology(陆地生态毒理学)see Ecotoxicology,Terrestrial

    Threshold Limit Value(阈限值)see Occupational Exposure Limits

    Toxicity Testing,Alternatives(选择性毒性试验)Shayne C Gad

    Toxicity Testing,Aquatic(水域毒性试验)Shayne C Gad

    Toxicity Testing,Behavioral(行为毒性试验)Samantha E Gad

    Toxicity Testing,Carcinogenesis(致癌毒性试验)Shayne O Gad

    Toxicity Testing,Dermal(皮肤毒性试验)Samantha E Gad and Shayne C Gad

    Toxicity Testing,Developmental(发育毒性试验)Rochelle W Tyl

    Toxicity Testing,Inhalation(吸人毒性试验)Samantha E Gad and Shayne C Gad

    Toxicity Testing,Irritation(刺激毒性试验)Pertti J Hakkinen

    Toxicity Testing,Modeling(模型化毒性试验)Charles A Pittinger,Andrew Worth,Joanna Jaworska and Joanne Shatkin

    Toxicity Testing,Mutagenicity(致突变毒性试验)Robin C Guy435

    Toxicity Testing,'Read Across Analysis'[识读交叉分析(毒性试验)]Pertti J

    Hakkinen

    Toxicity Testing,Reproductive(生殖毒性试验)Rochelle W Tyl

    Toxicity Testing,Sensitization(致敏毒性试验)Rob in C Guy

    Toxicity Testing,Validation(毒性试验验证)Leon H Bruner,G J Carr,M Chamb-

    erlain and R D Curren

    Toxicity,Acute(急性毒性)Donald J Ecobichon

    Toxicity,Chronic(长期毒性)Donald J Ecobichon

    Toxicity,Subchronic(亚慢性毒性)Donald J Ecobichon

    Toxicokinetics(毒物代谢动力学)see Pharmacokinetics/Toxicokinetics

    Toxicology(毒理学)Gabriel L Plaa

    Toxicology,Intuitive(直觉毒理学)Pertti J Hakkinen

    Uncertainty Analysis(不确定检验)Virginia Lau

    Uncertainty Factors(不确定系数)Michael Dourson

    Validation of Toxicity Testing(毒性试验验证)see Toxicity Testing,Validation

    Veterinary Toxicology(兽医毒理学)Wilson K Rumbeiha and Frederick W Oehme

    Virtually Safe Dose(VSD)(实际安全剂量)Stephen M DiZio

    拓展卷目录

    社科管理卷目录

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