|
|
|
 |
| 《基因与信号》 |
| 作者:(美)普坦森 等著 |
| 出版社：清华大学出版社 |
出版日期：2003-8-1 |
| ISBN：730206783X |
定价：32.5元 |
|
内容提要
我国的生命科学与生物技术和美国、日本等发达国家相比还有较大差距，存在生命科学基础理论研究不够深入扎实、学术创新能力不强、拥有自主知识产权的生物技术产品种类少、产量低、生物技术产业规模小、相关配套产业社会化程度低等问题。为了高等院校师生和广大科技人员借鉴和学习发达国家生命科学与技术的先进理论和技术，提高我国在生物经济方面的竞争力，我们精选了一批国外优秀生命科学与生物技术著作，组织专家进行了评阅和审核，希望能对高等院校师生和广大科技人员有所帮助，同时对我国生命科学和生物技术产业赶超世界先进水平起到一定的推动作用。
目录
Preface
Foreword
Introduction
CHAPTER 1 Lessons from Bacteria
RNA POLYMERASE
REGULATED RECRUITMENT:THE/ac GENES
Protein-DNA Interactions
Detecting Physiological Signals
promoter Recognition and Transcription by RNA Polymerase
Switching the Genes On:Activation by CAP
Cooperative Binding of Proteins to DNA
Cooperative Binding and Gene Activation by CAP
Repression by Lac Repressor
Interim Summary and Extension
MORE REGULATED RECRUITMENT:THE BACTERIOPHAGE
The Switch
Establishing Lysogeny
Analogies with lac
promoters
Protein-DNA interactions
Repression
Activation
Detecting Physiological Signals
Making an Efficient Switch
Cooperative Binding of Repressor to DNA
Autogenous Control by Repressor
PANEL:Antitermination:N and Q
Interim Summary and Extensions
Activation :A Closer Look
DNA binding:A Closer Look
Synergy
POLYMERASE ACTIVATION:glnA AND RELATED GENES
Promoter Recognition by containing Ploymerase
DNA Binding by NtrC
Detecing the Physiological Signal
Activation by NtrC
Other Activatjors of Polymerase
Interim Summary
PANEL:Phage T4 Late Genes
PROMOTER ACTIVATION:merT AND RELATED GENES
Promoter Recognition
Detection the Physiological and Activation
Interim Summary
GENERAL SUMMARY
PANEL:more on Repression in Bacteria
FOOTNOTES
BIBLIOGRAPHY
CHAPTER 2 Yeast:A single-celled Eukaryote……
CHAPTER 3 Some Note on Higher Eukaryotes
CHAPTER 4 Enyme Specificity and Regulation
Afterword
Appendices
Appendix1:More on Cooperativity
Apperdix2:Topogenic Sepuences
Appendix3:All-or-none Effects and Levels of Gene Expression
Index |
|
|