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《医学分子病毒学纲要-Key Notes on Medical Molecular Virology——博学·研究生系列》
作者:闻玉梅等 编著
出版社:复旦大学出版社 出版日期:2005-8-1
ISBN:730904598X 定价:28元
    内容提要

    This book provides a key for students to open the door to medical molecular virology, and therefore it only introduces the important themes of medical molecular virology. Questions are included between sections in all chapters, but with no "standard" answers. These questions are raised to prompt active and innovative discussion.

    The contents of this book are divided into two parts. The first 9 chapters introduce the important aspects of general medical molecular virology. Some chapters ask questions like "What is a virus?" "Are virus and cells interdependent?" "Is persistent virus infection a favorable balance?" "Why are there so many types of illterferons?" "Why is virus nomenclature important?" Other chapters describe viral oncogenesis,antiviral development, vaccines and prions. The latter three chapters describe selected individual viruses, which cover the RNA viruses(influenza virus, enteroviruses, Hantaan virus and flaviviruses), the RNA-DNA intermediate viruses (human immunodeficiency virus and hepatitis B virus), and DNA viruses (herpesviruses, human papilloma viruses,adenoviruses and poxviruses).

    It is hoped that by reading this book and by participating in discussions,the students will be interested in a further reading, and a list of reading materials is suggested at the end of each chapter.

    作者简介

    Yu-Mei Wen, graduated from Shanghai First Medical College, China, was a WHO Fellow at London School of Hygiene and Tropical Medicine, UK, and was a Fogarty FelIow at Hepatitis Viruses Section, Laboratory of Infectious Diseases, NlAID, National lnstitutes of Health, Bethesda,USA. Her main research interest is in molecular virology and immunology of hepatitis B virus, and published 210 articIes in journals home and abroad. She has been teaching virology to medical students for more than 30 years, and this book is written to stimulate original thinking in her students.

    Philip P Mortimer, former director of the Virus Reference Division of the Public Health Laboratory Service, UK. His main interest have been in blood borne viruses and in the application of technical advances in viraI diagnosis to clinical and public health problems. He has published 150 original

    articles and reviews in peer reviewed journals.

    Jia-you Zhang, associate professor at the Department of Microbiology, Immunology and Molecular Genetics,University of Kentucky, USA. Awarded PhD by the University of Texas at Austin. He was a postdoctoraI fellow under the tutorship of late Prof. Temin at the University of Wisconsin-Madison where he estabIished a model for formation of a transducing retrovirus by non-homologous recombination.His main interest is in retroviraI recombination. He has published papers in Science, Molecular CelluIar Biology and the Journal of Virology.

    目录

    Table of Contents

    Chapter 1 Is a virus just a packet of genes?

    Chapter 2 Viruses and host cells -- Are they interdependent?

    Chapter 3 Persistent virus infection -- a favorabIe balance or not?

    Chapter 4 Why are there so many types of intederons?

    Chapter 5 Viral oncogenesis -- an unexpected outcome of virus infection

    Chapter 6 Antiviral drug deveIopment -- hopes and disappointments

    Chapter 7 Vaccines -- an outstanding success

    Chapter 8 Prions -- a challenge to dogma

    Chapter 9 Why is virus nomenclature important?

    Chapter 10 RNA viruses

    10. 1 Influenza virus -- an example of virus mutations

    l0. 2 Enteroviruses -- multiple Organ-targeting

    l0. 3 Hantaan virus -- immunopathogenesis

    l0. 4 Flaviviruses -- the old and the new comes

    Chapter 11 RNA-DNA intermediate viruses

    11. 1 Human immunodeficiency -- a current plague

    11. 2 Hepatitis B virus -- a virus of great concern

    Chapter 12 DNA viruses

    l2. 1 Herpes viruses and viral latency

    l2. 2 Human papilloma viruses -- potetial for oncogenesis

    l2. 3 Adenovirus -- dual roles as a pathogen and a gene theray vector

    l2. 4 Poxviruses -- alert against bioterrorism