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《凯利风湿病学(英文原版)(1.2)》
作者:(美)路迪 著
出版社:人民卫生出版社 出版日期:2002-8-1
ISBN:7117049960 定价:510元
    内容提要

    More than 20 years ago, in the preface to the first edition of the Textbook of Rheumatology, we suggested that "The field of rheumatology has come of age." What we meant was that rheumatology had shed its strictly empirical base and its host of unproven remedies and become a healing discipline thoroughly grounded in science. We thought it was time for a new textbook, one that reflected this passage through epistemological puberty.

    The sixth edition reflects the maturation of rheumatology as a subspecialty. It is instructive to compare the contents of the first and sixth editions. Many chapters have disappeared entirely, and their material has been condensed and incorporated into existing chapters. Consider, for example, that in the basic science section of the first edition we devoted entire chapters to immunoglobulin structure, the contact activation system, and lysosomes (not to mention purine metabolism, a subject dear to the heart of the then senior editor). Cyclic nucleotides and eosinophilic chemotactic factor of anaphylaxis figured prominently in the titles of other basic science chapters. None of these has a place in the Table of Contents of the current edition. Instead, there are chapters dealing with dendritic cells, leukotrienes, mast cells, nitric oxide, fibroblasts, cytokines, and apoptosis. The importance of these topics to understanding the rheumatic diseases was unknown 20 years ago, and some of them hadn't even been discovered! Who can imagine what the scientific basis of rheumatology will be in the 10th edition, 20 years from now? Surely, knowledge obtained from the working through of the human genome will figure prominently.

    目录

    VOLUME 1

    Section 1 BIOLOGY OF THE NORMAL JOINT

    1. BIOLOGY OF THE NORMAL JOINT

    2. COLLAGEN AND ELASTIN

    3. MATRIX GLYCOPROTEINS,PROTEOGLYCANS,AND CARTILAGE

    4. PROTEINASES AND MATRIX DEGRADATION

    5. BIOMECHANICS OF JOINTS

    Section 2 IMMUNE AND INFLAMMATORY RESPONSES

    6. MACROPHAGES,DENDRITIC CELLS,AND FOLLICULAR DENDRITIC CELLS

    7. GENETICS OF RHEUMATIC DISEASES

    8. T LYMPHOCYTES

    9. B CELLS

    10. RHEUMATOID FACTOR

    11. ANTINUCLEAR ANTIBODIES

    12. IMMUNE COMPLEXES

    13. COMPLEMENT

    14. NEUTROPHILS AND EOSINOPHILS

    15. PROSTAGLANDINS,LEUKOTRIENES,AND RELATED COMPOUNDS

    16. THE MAST CELL

    17. ENDOTHELIAL CELLS AND NITRIC OXIDE

    18. PLATELETS

    19. FIBROBLAST FUNCTION AND FIBROSIS

    20. CYTOKINES

    21. APOPTOSIS

    22. AUTOMMUNITY

    Section 3 EVALUATION OF THE PATIENT

    23. EPIDEMIOLOGY OF THE RHEUMATIC DISEASES

    24. EVIDENCE-BASED RHEUMATOLOGY

    25. EXAMINATION OF THE JOINTS

    26. MONARTICULAR ARTHRITIS

    27. POLYARTICULAR ARTHRITIS

    28. WEAKNESS

    29. THE EYE AND RHEUMATIC DISEASE

    30. THE SKIN

    Section 4 MUSCULOSKELETAL PAIN AND EVALUATION

    31. FIBROMYALGIA

    32. OCCUPATIONAL AND RECREATIONAL MUSCULOSKELETAL DISORDERS

    33. SPORTS MEDICINE

    34. NECK PAIN

    35. SHOULDER PAIN

    36. LOW BACK PAIN

    37. HIP AND KNEE PAIN

    38. ANKLE AND FOOT PAIN

    39. TEMPOROMANDIBULAR JOINT PAIN

    40. HAND AND WRIST PAIN

    Section 5 DIAGNOSTIC TESTS AND PROCEDURES

    41. ASPIRATION AND INJECTION OF JOINTS AND SOFT TISSUES

    42. SYNOVIAL FLUID ANALYSIS AND SYNOVIAL BIOPSY

    43. IMAGING

    44. ARTHROSCOPY AND SYNOVECTOMY

    45. LABORATORY EVALUATION OF INFLAMMATION

    46. BIOLOGIC MARKERS

    Section 6 SPECIAL ISSUES

    47. NUTRITION AND RHEUMATIC DISEASES

    48. PSYCHOSOCIAL MANAGEMENT OF RHEUMATIC DISEASES

    49. GERIATRICS AND THE RHEUMATIC DISEASES

    50. ALTERNATIVE CARE FOR ARTHRITIS AND RELATED MUSCULOSKELETAL DISEASES

    51. CHRONIC PAIN MANAGEMENT

    52. REHABILITATION OF PATIENTS WITH RHEUMATIC DISEASES

    53. HEALTH OUTCOME ASSESSMENT

    Section 7 CLINICAL PHARMACOLOGY

    54. DEVELOPING A CLINICAL TRIAL DESIGN

    55. NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

    56. GLUCOCORTICOIDS

    57. METHOTREXATE

    58. SULFASALAZINE

    59. ANTIMALARIAL DRUGS

    60. GOLD AND PENICILLAMINE

    61. IMMUNOREGULATORY DRUGS

    62. BIOLOGIC AGENTS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS

    63. TETRACYCLINES

    INDEX

    VOLUME 2

    Section 8 RHEUMATOID ARTHRITIS

    Section 9 SPONDYLOARTHROPATHIES

    Section 10 SYSTEMIC LUPUS ERYTHEMATOSUS AND RELATED SYNDROMES

    Section 11 VASCULITIC SYNDROMES

    Section 12 SCLERODERMA AND MIXED CONNECTIVE TISSUE DISEASES

    Section 13 STRUCTURE,FUNCTION,AND DISEASE OF MUSCLE

    Section 14 RHEUMATIC DISEASES OF CHILDHOOD

    Section 15 CRYSTAL-ASSOCIATED SYNOVITIS

    Section 16 OSTEOARTHRITIS,POLYCHONDRITIS,AND HERITABLE DISORDERS

    Section 17 ARTHRITIS RELATED TO INFECTION

    Section 18 ARTHRITIS ACCOMPANYING SYSTEMIC DISORDERS

    Section 19 DISORDERS OF BONE AND STRUCTURAL PROTEIN

    Section 20 TUMORS INVOLVING JOINTS

    Section 21 RECONSTRUCTIVE SURGERY FOR RHEUMATIC DISEASE

    INDEX