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《癌症基因治疗学 英文原版》
作者:(美)拉蒂姆 著
出版社:人民卫生出版社 出版日期:2002-10-1
ISBN:711705105 定价:119元
    内容提要

    .

    目录

    Contributor

    Preface

    PARTⅠ VECTORS FOR GENE THERAPR OF CANCER

    1.Retroviral Vector Design for Cancer Gene Therapy

    2.Noninfections Gene Transfer and Expression Systems for Cancer Gene Therapy

    3.Parvovirus Vectors for the Gene Therapy of Cancer

    4.Antibody-Targeted Gene Therapy

    5.Ribozymes in Cancer Gene Therapy

    6.The Advent of Lentiviral Vectors:Prospects for Cancer Therapy

    PART Ⅱ IMMUNE TARGETIED GENE THERAPY

    7.Immunologic Targets for the Gene Therapy of Cancer

    PART Ⅱa VACCINE STRATEGIES

    8.Development of Eqitope-Specific Immunotherapies for Human Malignancies and Premalignant Lesions Expressing Mutated ras Genes

    PART Ⅱb DENDRITIC CELL-BASED GENE THERAPY

    9.Introduction to Dendritic Cells

    10.DNA and Dendritic Cell-Based Genetic Immunization Against Cancer

    11.RNA-Transfected Dendritic Cells as Immunogens

    PART Ⅱc CYTOKINES AND CO-FACTORS

    12.In Situ Immune Modulation Using Recombinatnt Vaccinia Virus Vectors:Preclinical Studies to Clinical Implementation

    13.The Use of Particle-Mediated Gene Transfer of Immunotherapy of Cance

    PART Ⅱd GENETICALLY MODIFIED EFFECTOR CELLS FOR IMMUNE-BASED IMMUNOTHERAPY

    14.Applications of Gene Transfer in the Adoptive Immunotherapy of Cancer

    15.Update on the Use of Genetically Modified Hematoppietic Stem Cells for Cancer Therapy

    PART Ⅲ ONCOGENE-TARGETED GENE THERAPY

    16.CLINICAL Applications of Tumor-Suppressor Gene Therapy

    17.Cancer Gene Therapy with Tumor Supperssor Genes Involved in Cell-Cycle Control

    18.Cancer Gene Therapy with the p53 Tumor Suppressor Gene

    19.Antisense Downregulation of the Apoptosis-Related Bcl-2and Bcl-xl Proteins:A New Approach to Cancer Therapy

    20.Gene Therpy for Chronic Myelogenous Leukemia

    PART Ⅳ MANULATION OF DRUG RESISTANCE MECHANISMS BY GENE THERARY……

    PART Ⅴ ANTI-ANIOGENESIS AND PRO-APORTOTIC GENE THERAPY

    PART Ⅵ PRODRUG ACTIVATION STRATEGIES FOR GENE THERAPY OF CANCER

    Index